Obtain serum T4 and TSH levels at the end of the trial period, and use laboratory test results and clinical assessment to guide diagnosis and treatment, if warranted. Limited published studies report that levothyroxine is present in human milk. Adequate buy levothyroxine sodium for research treatment during lactation may normalize milk production in hypothyroid lactating mothers. Thyroid hormone increases metabolic clearance of glucocorticoids. Initiation of thyroid hormone therapy prior to initiating glucocorticoid therapy may precipitate an acute adrenal crisis in patients with adrenal insufficiency.
- 7 As a result, many cardiac functions including heart rate, cardiac output, and systemic vascular resistance are closely linked to thyroid status.
- Addition of SYNTHROID therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements.
- It’s a synthetic version of the natural thyroid hormone called T4.
- In this case, you may not have enough Synthroid in your body to treat your condition.
- This includes prescription and over-the-counter medicines, vitamins, and herbal products.
It’s approved to treat hypothyroidism and to suppress (lower) levels of thyroid stimulating hormone (TSH). Below, we describe how Synthroid works for each of these uses. (The two main thyroid hormones in your body are T3 and T4.) In addition, TSH is responsible for growth of cells in your thyroid gland, including growth of cancerous cells. By decreasing your TSH level, Synthroid can help decrease the growth of certain types of thyroid cancer. To learn more about thyroid cancer, you can refer to our cancer hub.
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This is because there haven’t been any clinical trials that compare Synthroid or products containing levothyroxine to a placebo (treatment with no active drug). This lack of studies is due to the drug’s age and the FDA’s history of drug approval requirements (see “History of Synthroid” below). If you’re taking Synthroid with one of these anticoagulants, your doctor may decrease your dosage of the anticoagulant. This helps to lower your risk of having blood that’s too thin.
Mild side effects
Below is information on a use for Synthroid that’s not appropriate. For example, to give the drug to children or infants, Synthroid tablets can be crushed and dissolved in 1 to 2 teaspoons (5 to 10 mL) of water. If you dissolve the drug like this, you’ll need to give the dose to the infant or child right away. This product may bind to Synthroid inside your stomach and lower the amount of Synthroid your body absorbs. In this case, you may not have enough Synthroid in your body to treat your condition. Some drugs used to treat depression may interact with Synthroid.
Synthroid for other conditions
This effect is usually temporary as your body adjusts to this medication. If this effect lasts or gets worse, tell your doctor or pharmacist promptly. If you are taking any of these drugs, separate them from this medication by at least 4 hours. If you switch from a brand-name to a generic preparation, you may notice that you don’t feel as well on the generic drug.
